In a recent article, provided by
HealthDay, and titled In Mice, Cancer Drug Shows Effect on Alzheimer’s Symptoms
(read article here), I read some pretty interesting news. Alzheimer’s is a
disease that affects people all over the world, and can be one of the hardest
diseases to deal with as a family member. (Read more about Alzheimer’s here). The
article talks about the drug, bexarotene, which quickly eliminates Alzheimer’s
disease related amyloid beta from the brain and reverses memory problems in
mice.
The article states the results
suggest that the drug could possibly help the many Americans (about 5.4
million!) that have Alzheimer’s disease according to the neuroscientists at
Case Western Reserve University School of Medicine. Although the studies of
using the drug bexarotene, which is a drug that is used to treat skin problems
caused by cutaneous T-cell lymphoma, to lessen the effects of Alzheimer’s on
animals, a lot of times they fail to produce similar results in humans.
When the
body is unable to clear amyloid beta from the brain is a big risk factor for
the development of Alzheimer’s disease. Research has showed that the main
cholesterol carrier in the brain, apolipoportein E, plays an important role in
the clearing amyloid beta proteins. Bexarotene increased the release of the
apolipoprotein which then boosted the clearance of amyloid beta from the brain.
Six hours after the mice received bexarotene treatment, levels of amyloid fell
by twenty five percent.
Even though
at this time, studies have not been conducted on humans, the study is still
very promising because it says that there just may be treatment for the devastating
disease! I have not personally had
anyone of my family members affected by this awful disease, but I have seen
friends go through this disease with their family members, and it is just awful
to see and hear how much Alzheimer’s in someone you love. After doing a little outside research, I found this website that talks about how to cope with Alzheimer's when a family member has the disease. Read that website here.
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